Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the TollLike Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma

Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the main causes of cancer death around the world. The activation of the differentiation of the 4 / myeloid receiver type main response gene 88 / nuclear factor-κB (TLR4 / MyD88 / NF-κB) contributes to the development and progression of HCC. The ubiquitine-proteasome system regulates the TLR4 expression. However, if the PEPTIDASE 13 (USP13) specific to Ubiquitin (USP13) stabilizes TLR4 and facilitates the progression of HCC remains uncertain.

Here, a quantitative analysis of real-time PCR (QRT-PCR) and immunohistochemistry revealed that the USP13 expression in HCC tissues was greater than that of non-tumor focoise tissues. In addition, the high expression of USP13 was detected in HCC cells (SK-HEP-1, HEPG2, HUH7 and HEP3B) relative to LO2 cells. Interestingly, the positive staining of USP13 was closely correlated at the tumor size ≥ 5 cm and at the stage of the advanced tumor and conferred on a significantly lower survival of patients with SCH. Then, USP13 Hashingdown has significantly reduced proliferation, epithelial-messenchymatory transition (EMT), migration and invasion of HEP3B and HUH7 cells, while USP13 overexpression improved these biological behaviors of HEPG2 and LO2 cells.

The silence of USP13 has significantly limited the growth and pulmonary metastasis of HCC cells in vivo. Mechanically, USP13 depletion significantly marked the TLR4 / MYD88 / NF-κB channel in HCC cells. USP13 interacted with TLR4 and inhibited the degradation of the Ubiquitine-mediated TLR4. Significantly, the TLR4 re-expression remarkably reversed the effects of USP13 isolation on HCC cells. The USP13 expression was clearly regulated in HCC cells under hypoxia conditions. NOTABLY, USP13 BULLDOWN has repressed the activation induced by hypoxia of the TLR4 / MYD88 / NF-κB channel in HCC cells. In conclusion, our study discovered that the USP13 induced by hypoxia facilitated HCC progression through the improvement of TLR4 desubility and the subsequent activation of the TLR4 / MYD88 / NF-KB channel.

 

Preparation of anti-em> toll </ em> – <em> like </ em> <em> </ em> – <em> 4 </ em> nano-antibodies and its effect on the negative sepsy of Gram negative

The essence of sepsis is the excessive immune response caused by infectious factors, resulting in the release of a large number of inflammatory factors and the injury of tissues and organs. Once the reaction is triggered, it will develop according to its own rules and will not depend on infection factors. The occurrence and severity of sepsis depend entirely on the body’s reaction. When pathogens invade the body, they rely on pattern recognition receivers to play a defensive role, TLR4 is the main switch of innate immunity. Current research shows that the LPS can induce the subsequent regulation of TLR4 gene expression in monocytes, neutrophils and other immune cells. The regulated TLR4, as a new receiver, mediate more cell activation and the release of inflammatory mediators.

Under this positive return, the inflammatory response is constantly amplified, which finally leads to the development of sepsis. In this study, the TLR4 extracellular domain antigen was obtained by the expression and purification of proteins, as well as the anti-TLR4 C-terminal and intermediate domain nano-antibody were obtained by the technology for preparing the Anti-phage antibody library. The in vitro and in vivo experiments confirmed that anti-TLR4 antibody can effectively reduce the release of inflammatory factors and improve the survival rate of animals, while the C-terminal and intermediate terminal are closed at the same time, The effect is more obvious. . The clinical treatment of sepsis provides new ideas and strategies.

 Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em>/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma
Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the TollLike Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma

Activation of <em> toll </ em> <em> as </ em> <em> </ em> <em> 4 </ em> (TLR <em> 4 </ em>) promotes apoptosis cardiomyocyte through Sirt2 dependent p53 deacetylation

Cardiomyocyte inflammation followed by apoptosis and fibrosis is an important mediator for the development and progression of heart failure. Activating the type 4 receptor (TLR4), an important inflammation regulator, causes progression of cardiac hypertrophy and injury. However, the precise mechanism of the adverse cardiac results of the TLR4 is still elusive. This study was designed to find the role of TLR4 in cardiac fibrosis and apoptosis and its molecular mechanism.

The rats were treated with a TLR4 agonist (LPS 12.5 μg / kg / day) by the osmotic pump for 14 days. To simulate the in vitro condition, H9C2 cells were treated with LPS (1 μg / ml). Similarly, H9C2 cells were transfected with the TLR4 and Sirt2 C-DNA clone for overexpression. The oxidative stress of myocardial, inflammation, fibrosis and mitochondrial parameters have been evaluated both in vitro and in vivo. Cardiac inflammation after the treatment of LPS has been confirmed by an increased expression of TNF-α and IL-6 in the rat’s heart. There was a marked increase in oxidative stress as observed by the increase of the Tbars and a decrease in endogenous antioxidants (GSH and Catalase), as well as mitochondrial dysfunction, as measured by a mitochondrial complex activity in the hearts of rats treated by The LPS. Histopathological examination showed the presence of cardiac fibrosis after the treatment of LPS. The expression of proteins of the nuclear P53 and CASPASE-7-7 / CASPASE-9 has been considerably increased in the LP-treated heart.

Vasopressin V1b Receptor (AVPR1B) Antibody

abx030536-80l 80 µl
EUR 343.2

Vasopressin V1b Receptor (AVPR1B) Antibody

abx119677-100l 100 µl
EUR 312.5

Vasopressin V1b Receptor (AVPR1B) Antibody

abx119677-20l 20 µl
EUR 43.75

Vasopressin V1b Receptor (AVPR1B) Antibody

abx119677-50l 50 µl
EUR 237.5

Vasopressin V1b Receptor (AVPR1B) Antibody

abx030536-400l 400 µl
EUR 518.75

Vasopressin V1b Receptor (AVPR1B) Antibody

abx027766-400l 400 µl
EUR 518.75

Vasopressin V1b receptor (AVPR1B) Antibody

abx341324-100l 100 µl
EUR 350

Vasopressin V1b receptor (AVPR1B) Antibody

abx341324-50l 50 µl
EUR 250

Vasopressin V1b receptor (AVPR1B) Antibody (HRP)

abx341325-100l 100 µl
EUR 350

Vasopressin V1b receptor (AVPR1B) Antibody (HRP)

abx341325-50l 50 µl
EUR 250

Vasopressin V1b receptor (AVPR1B) Antibody (FITC)

abx341326-100g 100 µg Ask for price

Vasopressin V1b receptor (AVPR1B) Antibody (FITC)

abx341326-20g 20 µg
EUR 250

Vasopressin V1b receptor (AVPR1B) Antibody (FITC)

abx341326-50g 50 µg
EUR 350

Vasopressin V1b receptor (AVPR1B) Antibody (Biotin)

abx341327-100g 100 µg Ask for price

Vasopressin V1b receptor (AVPR1B) Antibody (Biotin)

abx341327-20g 20 µg
EUR 250

Vasopressin V1b receptor (AVPR1B) Antibody (Biotin)

abx341327-50g 50 µg
EUR 350

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

20-abx326883
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

20-abx324233
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

20-abx175466
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

20-abx175467
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

20-abx110673
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

abx110673-100l 100 µl
EUR 162.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

abx326883-100g 100 µg
EUR 250

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

abx326883-50g 50 µg
EUR 187.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

abx324233-100g 100 µg
EUR 250

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody

abx324233-50g 50 µg
EUR 187.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (HRP)

20-abx109236
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (HRP)

abx109236-100l 100 µl
EUR 162.5

AVPR1B (untagged)-Human arginine vasopressin receptor 1B (AVPR1B)

SC128112 10 µg Ask for price

AVP Receptor V3 Polyclonal Antibody

E046878 100μg/100μl
EUR 255
Description: Available in various conjugation types.

AVP Receptor V3 Polyclonal Antibody

E11-2036001 100ug/100ul
EUR 225
Description: Available in various conjugation types.

AVP Receptor V3 Polyclonal Antibody

E20-70424 100ug
EUR 225
Description: Available in various conjugation types.

AVP Receptor V3 Polyclonal Antibody

46878 100ul
EUR 319

AVP Receptor V3 Polyclonal Antibody

46878-100ul 100ul
EUR 302.4

AVP Receptor V3 Polyclonal Antibody

46878-50ul 50ul
EUR 224.4

AVP Receptor V3 Polyclonal Antibody

ABP57860-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human, Mouse, Rat. This AVP Receptor V3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AVP Receptor V3 protein at amino acid sequence of 271-320

AVP Receptor V3 Polyclonal Antibody

ABP57860-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human, Mouse, Rat. This AVP Receptor V3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AVP Receptor V3 protein at amino acid sequence of 271-320

AVP Receptor V3 Polyclonal Antibody

ABP57860-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human, Mouse, Rat. This AVP Receptor V3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AVP Receptor V3 protein at amino acid sequence of 271-320

AVP Receptor V3 Polyclonal Antibody

ABP50738-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human. This AVP Receptor V3 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AVP Receptor V3 at AA range: 250-330

AVP Receptor V3 Polyclonal Antibody

ABP50738-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human. This AVP Receptor V3 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AVP Receptor V3 at AA range: 250-330

AVP Receptor V3 Polyclonal Antibody

ABP50738-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AVP Receptor V3 from Human. This AVP Receptor V3 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AVP Receptor V3 at AA range: 250-330

AVP Receptor V3 Polyclonal Antibody

E44H07443 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

AVP Receptor V3 Polyclonal Antibody

E44H04078 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (FITC)

20-abx107819
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (FITC)

abx107819-100g 100 µg
EUR 362.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (FITC)

abx107819-20g 20 µg
EUR 162.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (FITC)

abx107819-50g 50 µg
EUR 250

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (Biotin)

20-abx106407
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Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (Biotin)

abx106407-100g 100 µg
EUR 362.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (Biotin)

abx106407-20g 20 µg
EUR 162.5

Arginine Vasopressin Receptor 1B (AVPR1B) Antibody (Biotin)

abx106407-50g 50 µg
EUR 250

AVPR1B (GFP-tagged) - Human arginine vasopressin receptor 1B (AVPR1B)

RG215919 10 µg Ask for price

Avpr1b (untagged) - Mouse arginine vasopressin receptor 1B (Avpr1b), (10ug)

MC209710 10 µg Ask for price

Arginine Vasopressin Receptor 1B (AVPR1B) Polyclonal Antibody

CAU31374-100ul 100ul
EUR 241.9

Arginine Vasopressin Receptor 1B (AVPR1B) Polyclonal Antibody

CAU31374-200ul 200ul
EUR 302.4

Avpr1b (GFP-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b), (10ug)

MG217375 10 µg Ask for price

Avpr1b (Myc-DDK-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b)

MR217375 10 µg Ask for price

AVPR1B (Myc-DDK-tagged)-Human arginine vasopressin receptor 1B (AVPR1B)

RC215919 10 µg Ask for price

Avpr1b (untagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), (10 ug)

RN203977 10 µg Ask for price

AVP Receptor V3 Rabbit Polyclonal Antibody

ES1737-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against AVP Receptor V3 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AVP Receptor V3 Rabbit Polyclonal Antibody

ES1737-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against AVP Receptor V3 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AVP Receptor V3 Rabbit Polyclonal Antibody

ES8759-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against AVP Receptor V3 from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

AVP Receptor V3 Rabbit Polyclonal Antibody

ES8759-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against AVP Receptor V3 from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

Rat Vasopressin V1b receptor (Avpr1b)

1-CSB-RP156394r(A4)
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Description: Recombinant Rat Vasopressin V1b receptor(Avpr1b),partial expressed in E.coli

Vasopressin V1b receptor (AVPR1B) (C-term) goat polyclonal antibody

GT41005-100 100 µg Ask for price

AVP Receptor V3 Polyclonal Conjugated Antibody

C46878 100ul
EUR 476.4

Avpr1b (Myc-DDK-tagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), (10 ug)

RR203977 10 µg Ask for price

Vasopressin V1b receptor (AVPR1B) rabbit polyclonal antibody, Aff - Purified

AP01341PU-N 100 µg Ask for price

Lenti ORF clone of Avpr1b (mGFP-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b)

MR217375L4 10 µg Ask for price

Lenti ORF clone of Avpr1b (Myc-DDK-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b)

MR217375L3 10 µg Ask for price

Rat Avpr1b/ Vasopressin V1b receptor ELISA Kit

E0110Ra 1 Kit
EUR 557
Description: AVPR V1b,AVPR V3,Antidiuretic hormone receptor 1b,Vasopressin V3 receptor

Rat Avpr1b(Vasopressin V1b receptor) ELISA Kit

ER0695 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Rat Vasopressin V1b receptor (AVPR1B) ELISA Kit

abx520989-96tests 96 tests
EUR 886.8

Rat Vasopressin V1b receptor(Avpr1b) ELISA Kit

YLA1672RA-48T 48T Ask for price

Rat Vasopressin V1b receptor(Avpr1b) ELISA Kit

YLA1672RA-96T 96T Ask for price

Rat Vasopressin V1b receptor (AVPR1B) ELISA Kit

abx256670-1096tests 10 × 96 tests Ask for price

Rat Vasopressin V1b receptor (AVPR1B) ELISA Kit

abx256670-596tests 5 × 96 tests Ask for price

Rat Avpr1b / Vasopressin V1b receptor ELISA Kit

E9135r 96T
EUR 796

Lenti ORF clone of Avpr1b (mGFP-tagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), (10 ug)

RR203977L4 10 µg Ask for price

Recombinant Human Vasopressin V1b receptor (AVPR1B)

CSB-CF002469HU(A4) 11242 mg Ask for price

Mouse Avpr1b/ Vasopressin V1b receptor ELISA Kit

E0151Mo 1 Kit
EUR 543
Description: V1br,AVPR V1b,AVPR V3,Antidiuretic hormone receptor 1b,Vasopressin V3 receptor

Human AVPR1B/ Vasopressin V1b receptor ELISA Kit

E0239Hu 1 Kit
EUR 515
Description: AVPR3,VPR3,AVPR V1b,AVPR V3,Antidiuretic hormone receptor 1b,Vasopressin V3 receptor

Human Vasopressin V1b receptor, AVPR1B ELISA KIT

ELI-07674h 96 Tests
EUR 988.8

Mouse Vasopressin V1b receptor, Avpr1b ELISA KIT

ELI-07675m 96 Tests
EUR 1038

Human AVPR1B(Vasopressin V1b receptor) ELISA Kit

EH2440 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Mouse Avpr1b/Vasopressin V1b receptor ELISA Kit

EK20028 96Т
EUR 650

Mouse Vasopressin V1b receptor (AVPR1B) ELISA Kit

abx572461-96tests 96 tests
EUR 886.8

Human Vasopressin V1b receptor (AVPR1B) ELISA Kit

abx251804-96tests 96 tests
EUR 886.8

Mouse Vasopressin V1b receptor (AVPR1B) ELISA Kit

RK13669 96T
EUR 280

Human Vasopressin V1b receptor (AVPR1B) ELISA Kit

RK12214 96T
EUR 280

Human Vasopressin V1b receptor(Avpr1b) ELISA Kit

YLA4334HU-48T 48T Ask for price

Human Vasopressin V1b receptor(Avpr1b) ELISA Kit

YLA4334HU-96T 96T Ask for price

Human AVPR1B / Vasopressin V1b receptor ELISA Kit

E9135h 96T
EUR 736

Mouse Avpr1b / Vasopressin V1b receptor ELISA Kit

E9135m 96T
EUR 776

Lenti ORF particles, Avpr1b (GFP-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b), 200ul, >10^7 TU/mL

MR217375L4V 200 µl Ask for price

Lenti ORF particles, AVPR1B (mGFP-tagged) - Human arginine vasopressin receptor 1B (AVPR1B), 200ul, >10^7 TU/mL

RC215919L2V 200 µl Ask for price

Lenti ORF particles, AVPR1B (mGFP-tagged) - Human arginine vasopressin receptor 1B (AVPR1B), 200ul, >10^7 TU/mL

RC215919L4V 200 µl Ask for price

Lenti ORF particles, Avpr1b (GFP-tagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), 200ul, >10^7 TU/mL

RR203977L4V 200 µl Ask for price

Rat Vasopressin V1b Receptor, AVPR1B GENLISA ELISA

KLR1478 1 x 96 wells
EUR 341

Vasopressin V1B Receptor (AVPR1B) Goat anti-Human Polyclonal (C-Terminus) Antibody

GWB-DF1D8F 0.05 mg Ask for price

AVP Receptor V3 Rabbit pAb

E2252488 100ul
EUR 225
Description: Available in various conjugation types.

Lenti ORF clone of Avpr1b (Myc-DDK-tagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), (10 ug)

RR203977L3 10 µg Ask for price

Lenti ORF particles, AVPR1B (Myc-DDK tagged) - Human arginine vasopressin receptor 1B (AVPR1B), 200ul, >10^7 TU/mL

RC215919L1V 200 µl Ask for price

Lenti ORF particles, AVPR1B (Myc-DDK tagged) - Human arginine vasopressin receptor 1B (AVPR1B), 200ul, >10^7 TU/mL

RC215919L3V 200 µl Ask for price

Lenti ORF particles, Avpr1b (Myc-DDK-tagged) - Mouse arginine vasopressin receptor 1B (Avpr1b), 200ul, >10^7 TU/mL

MR217375L3V 200 µl Ask for price

Mouse Arginine Vasopressin Receptor 1B (AVPR1B) Protein

20-abx652577
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Mouse Arginine Vasopressin Receptor 1B (AVPR1B) Protein

20-abx652578
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Mouse Arginine Vasopressin Receptor 1B (AVPR1B) Protein

abx652577-5mg 5 mg
EUR 4525

Lenti ORF particles, Avpr1b (Myc-DDK-tagged ORF) - Rat arginine vasopressin receptor 1B (Avpr1b), 200ul, >10^7 TU/mL

RR203977L3V 200 µl Ask for price

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

CPB263Hu21 10ug
EUR 120

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

4-CPB263Hu21
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  • 100 ug
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  • 1 mg
  • 200 ug
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  • 50ug
  • 5 mg
Description: Recombinant Human Arginine Vasopressin Receptor 1B expressed in: chemical synthesis

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

RPU50083-100ug 100ug
EUR 475.2

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

RPU50083-1mg 1mg
EUR 1872

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

RPU50083-50ug 50ug
EUR 288

Recombinant Rat Vasopressin V1b receptor (Avpr1b), partial

CSB-EP002469RA1 5367 mg Ask for price

Recombinant Rat Vasopressin V1b receptor(Avpr1b),partial

AP72299 1mg
EUR 2826

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DLR-AVPR1B-Ra 96T
EUR 477
Description: tissue homogenates or other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DLR-AVPR1B-Ra-48T 48T
EUR 633.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Arginine Vasopressin Receptor 1B (AVPR1B) in samples from tissue homogenates or other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DLR-AVPR1B-Ra-96T 96T
EUR 828
Description: A sandwich quantitative ELISA assay kit for detection of Rat Arginine Vasopressin Receptor 1B (AVPR1B) in samples from tissue homogenates or other biological fluids.

Rat AVPR1B(Arginine Vasopressin Receptor 1B) ELISA Kit

ELK8886-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat AVPR1B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat AVPR1B. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat AVPR1B, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat AVPR1B in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat AVPR1B(Arginine Vasopressin Receptor 1B) ELISA Kit

ELK8886-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat AVPR1B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat AVPR1B. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat AVPR1B, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat AVPR1B in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DL-AVPR1B-Ra 96T
EUR 454
Description: tissue homogenates or other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

EK17421 96Т
EUR 768

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RDR-AVPR1B-Ra-48T 48T
EUR 488.78
Description: tissue homogenates and other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RDR-AVPR1B-Ra-48Tests 48 Tests
EUR 669.6

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RDR-AVPR1B-Ra-96T 96T
EUR 698.25
Description: tissue homogenates and other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RDR-AVPR1B-Ra-96Tests 96 Tests
EUR 931.2

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RD-AVPR1B-Ra-48T 48T
EUR 465.5
Description: tissue homogenates and other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RD-AVPR1B-Ra-48Tests 48 Tests
EUR 640.8

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RD-AVPR1B-Ra-96T 96T
EUR 665
Description: tissue homogenates and other biological fluids.

Rat Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

RD-AVPR1B-Ra-96Tests 96 Tests
EUR 890.4

Mouse Arginine Vasopressin Receptor 1B (AVPR1B) CLIA Kit

20-abx492563
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DLR-AVPR1B-Hu 96T
EUR 443
Description: tissue homogenates or other biological fluids.

Human Arginine Vasopressin Receptor 1B (AVPR1B) ELISA Kit

DLR-AVPR1B-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Arginine Vasopressin Receptor 1B (AVPR1B) in samples from tissue homogenates or other biological fluids.

Similar to in vivo study, the nuclear translocation of P53, mitochondrial and cell apoptosis dysfunction were observed in the H9C2 cells treated with LPS. Our data also indicates that SIRT2 reduced expression was associated with an increase in acetylation of P53 after the treatment of the LPS. In conclusion, TLR4 activation in rats promotes cardiac inflammation, mitochondrial dysfunction, apoptosis and fibrosis. P53 and CASPASE 7 / CASPASE 9 were found to play an important role in the apoptosis mediated by TLR4. Our data suggest that TLR4-mediated fibrosis reduction and apoptosis could be a new approach in the treatment of heart failure, taking into account the major role played by TLR4 in cardiac inflammation.

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