Toll–Like Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

Although vascular dysfunction is a key event in the development of diabetic complications, and abnormal pulse like receptor 4 (TLR4) may contribute to the pathophysiology of vascular disease, a direct link between TLR4 and function of blood vessels in the arterial diabetes remains poorly understood. Thus, to investigate whether pharmacological blockade of TLR4 affect blood vessel function in the superior mesenteric artery (SMA) of streptozotocin (STZ) -induced diabetic rats, SMA isolated from male Wistar rats were injected once with STZ (65 mg / kg, 27 – 34 weeks) treated with TAK-242 (10-6 M), TLR4 inhibitor, for about 1 d using organ culture techniques.

After incubation, functional and biochemical studies performed. In functional studies, treatment with TAK-242 increased by acetylcholine (ACh) induced relaxation of SMA diabetes in the intact condition. Sodium nitroprusside (SNP) induced relaxation was also increased in the group of TAK-242-treated compared to vehicle-treated group. Under the cyclooxygenase (COX) blockade by indomethacin (10-5 M), Ach-induced relaxation was similar in-vehicle group and TAK-242-treated.

Additionally, ACh-induced relaxation in the presence of a combination of nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine (L-NNA) (10-4 M) and indomethacin (10-5 M) were similar in the group vehicle-and TAK-242-treated. Productions of thromboxane (TX) B2 in the culture medium in the presence of ACh (10-5 M) was lower in the group of TAK-242-treated compared to vehicle-treated group.

These data show that the TAK-242 could improve endothelium-dependent relaxation by partially suppress TXA2 vasoconstrictor or increase NO signal. TLR4 inhibition may be a new therapeutic strategy to assist in the management of vascular complications associated with diabetes.

 <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em> Inhibitor TAK-2<em>4</em>2 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat
TollLike Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

high group mobility boxes-1 induces mechanical pain hypersensitivity through connexin astrocytic 4 3 through Tol – like receptor – < em> 4 / JNK signaling pathway

This study aimed to investigate the effect of box-1-high mobility group (HMGB-1) on the mechanical pain and hypersensitivity underlying mechanisms. Rat primary astrocytes were isolated and treated as specified. A CCK-8 assay was used to determine cytotoxicity and test gap junctional communication is done. Ethidium bromide (EtBr) uptake is used to evaluate the activity hemichannel primary astrocytes.

A rat model of neuropathic pain developed and foot withdrawal thresholds used to evaluate the sensitivity of its hind legs. RT-qPCR and Western blot was used to determine the mRNA and protein expression of the gene, respectively. ELISA was used to measure the release of inflammatory cytokines. Treatment with HMGB-1 increased the expression of both pulses like receptor-4 (TLR-4) and connexin 43 (Cx43) in rat primary astrocytes. HMGB-1 also promoted gap junctional communication between cells and function hemichannel.

Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-100g 100 µg
EUR 537.5

Mouse Toll Like Receptor 2 (TLR2) Protein

20-abx167213
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  • 10 ug
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  • 1 mg

Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-10g 10 µg
EUR 212.5

Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-50g 50 µg
EUR 375

Mouse Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491847
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  • 96 tests
  • 5 × 96 tests
  • 10 × 96 tests

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

abx575343-96tests 96 tests
EUR 801.6

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu 96T
EUR 432
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu-48T 48T
EUR 586.8
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu-96T 96T
EUR 762
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DL-TLR2-Mu 96T
EUR 412
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

abx254557-96tests 96 tests
EUR 562.5

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

20-abx154784
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  • 96 tests
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Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-48T 48T
EUR 514.08

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-5x96T 5x96T
EUR 3488.4

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-96T 96T
EUR 734.4

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EK16960 96Т
EUR 768

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-48T 48T
EUR 350.42

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-5x96T 5x96T
EUR 2377.85

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-96T 96T
EUR 500.6

Mouse Toll- like receptor 2, Tlr2 ELISA KIT

ELI-02327m 96 Tests
EUR 1038

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS4502934-10x96Tests 10x96Tests
EUR 4965

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS4502934-48Tests 48Tests
EUR 435

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS4502934-5x96Tests 5x96Tests
EUR 2550

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS4502934-96Test 96Test
EUR 575

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2020869-10x96StripWells 10x96-Strip-Wells
EUR 4995

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2020869-24StripWells 24-Strip-Wells
EUR 345

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2020869-48StripWells 48-Strip-Wells
EUR 510

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2020869-5x96StripWells 5x96-Strip-Wells
EUR 2735

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2020869-96StripWells 96-Strip-Wells
EUR 680

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS455148-10x96StripWells 10x96-Strip-Wells
EUR 4800

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS455148-48StripWells 48-Strip-Wells
EUR 420

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS455148-5x96StripWells 5x96-Strip-Wells
EUR 2465

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS455148-96StripWells 96-Strip-Wells
EUR 550

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2702239-10x96StripWells 10x96-Strip-Wells
EUR 2905

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2702239-24StripWells 24-Strip-Wells
EUR 240

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2702239-48StripWells 48-Strip-Wells
EUR 320

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2702239-5x96StripWells 5x96-Strip-Wells
EUR 1515

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS2702239-96StripWells 96-Strip-Wells
EUR 390

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS9309620-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS9309620-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS9309620-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

MBS9309620-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-48T 48T
EUR 465
Description: sandwich

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-48Tests 48 Tests
EUR 613.2

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-96T 96T
EUR 665
Description: sandwich

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-96Tests 96 Tests
EUR 850.8

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-48T 48T
EUR 443
Description: sandwich

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-48Tests 48 Tests
EUR 586.8

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-96T 96T
EUR 633
Description: sandwich

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-96Tests 96 Tests
EUR 812.4

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SL0779Mo -
EUR 528

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-10x96wellstestplate 10x96-wells test plate
EUR 5269.39
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x48wellstestplate 1x48-wells test plate
EUR 539.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x96wellstestplate 1x96-wells test plate
EUR 718.75
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-5x96wellstestplate 5x96-wells test plate
EUR 2874.38
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Mu
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse)

4-PAA663Mu01
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2)

Mouse Toll Like Receptor 2, TLR2 GENLISA ELISA    

KLM0401 1 x 96 wells
EUR 341

Mouse Toll Like Receptor 2-TLR2-ELISA Kit

QY-E21479 96T
EUR 400

Mouse TLR2 (Toll Like Receptor 2) ELISA Kit

MBS8801667-10x96StripWells 10x96-Strip-Wells
EUR 3130

Mouse TLR2 (Toll Like Receptor 2) ELISA Kit

MBS8801667-48StripWells 48-Strip-Wells
EUR 350

Mouse TLR2 (Toll Like Receptor 2) ELISA Kit

MBS8801667-5x96StripWells 5x96-Strip-Wells
EUR 1710

Mouse TLR2 (Toll Like Receptor 2) ELISA Kit

MBS8801667-96StripWells 96-Strip-Wells
EUR 445

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), PE

4-PAA663Mu01-PE
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with PE.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), APC

4-PAA663Mu01-APC
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with APC.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Cy3

4-PAA663Mu01-Cy3
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Cy3.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), HRP

4-PAA663Mu01-HRP
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with HRP.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), FITC

4-PAA663Mu01-FITC
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with FITC.

Toll Like Receptor 2 (TLR2) Antibody

abx001983-100l 100 µl
EUR 400

Toll Like Receptor 2 (TLR2) Antibody

abx001983-20l 20 µl
EUR 175

Toll Like Receptor 2 (TLR2) Antibody

abx001983-50l 50 µl
EUR 275

Toll Like Receptor 2 (TLR2) Antibody

abx027542-400l 400 µl
EUR 518.75

Toll Like Receptor 2 (TLR2) Antibody

abx027542-80l 80 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx028479-400l 400 µl
EUR 518.75

Toll Like Receptor 2 (TLR2) Antibody

abx028479-80l 80 µl
EUR 281.25

Toll Like Receptor 2 (TLR2) Antibody

abx028480-400l 400 µl
EUR 525

Toll Like Receptor 2 (TLR2) Antibody

abx028480-80l 80 µl
EUR 281.25

Toll Like Receptor 2 (TLR2) Antibody

abx011833-100g 100 µg Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx011833-10g 10 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody

abx011833-200g 200 µg Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx212686-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

20-abx212686
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Toll Like Receptor 2 (TLR2) Antibody

abx212686-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx212687-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

20-abx212687
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Toll Like Receptor 2 (TLR2) Antibody

abx212687-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx102058-100l 100 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

20-abx102058
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Toll Like Receptor 2 (TLR2) Antibody

abx102058-1ml 1 ml
EUR 675

Toll Like Receptor 2 (TLR2) Antibody

abx102058-200l 200 µl
EUR 312.5

Toll Like Receptor 2 (TLR2) Antibody

abx102059-100l 100 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

20-abx102059
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Toll Like Receptor 2 (TLR2) Antibody

abx102059-1ml 1 ml
EUR 675

Toll Like Receptor 2 (TLR2) Antibody

abx102059-200l 200 µl
EUR 312.5

Toll Like Receptor 2 (TLR2) Antibody

abx102060-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx102060
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Toll Like Receptor 2 (TLR2) Antibody

abx102060-1ml 1 ml
EUR 712.5

Toll Like Receptor 2 (TLR2) Antibody

abx102060-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx102061-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx102061
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  • 20 ug
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Toll Like Receptor 2 (TLR2) Antibody

abx102061-1ml 1 ml
EUR 712.5

Toll Like Receptor 2 (TLR2) Antibody

abx102061-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx102062-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx102062
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Toll Like Receptor 2 (TLR2) Antibody

abx102062-1ml 1 ml
EUR 725

Toll Like Receptor 2 (TLR2) Antibody

abx102062-200l 200 µl
EUR 337.5

Toll Like Receptor 2 (TLR2) Antibody

abx110267-100l 100 µl
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody

abx137432-100tests 100 tests
EUR 225

Toll Like Receptor 2 (TLR2) Antibody

abx129332-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx129332
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Toll Like Receptor 2 (TLR2) Antibody

abx129332-1ml 1 ml
EUR 687.5

Toll Like Receptor 2 (TLR2) Antibody

abx129332-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx412013-100g 100 µg
EUR 462.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx174839
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  • 200 ug
  • 1 mg

Toll Like Receptor 2 (TLR2) Antibody

abx174839-25g 25 g
EUR 775

Toll Like Receptor 2 (TLR2) Antibody

abx326823-100g 100 µg
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

20-abx326823
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Toll Like Receptor 2 (TLR2) Antibody

abx326823-50g 50 µg
EUR 187.5

Toll Like Receptor 2 (TLR2) Antibody

20-abx178628
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  • 200 ug
  • 1 mg

Toll Like Receptor 2 (TLR2) Antibody

abx212302-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

20-abx212302
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Toll Like Receptor 2 (TLR2) Antibody

abx212302-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx212303-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

20-abx212303
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Toll Like Receptor 2 (TLR2) Antibody

abx212303-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx239892-100l 100 µl Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx239892-50l 50 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx147259-1096tests 10 × 96 tests Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx147259-596tests 5 × 96 tests Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx147259-96tests 96 tests
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

20-abx270107
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  • 25 tests
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Toll Like Receptor 2 (TLR2) Antibody

abx270107-1ml 1 ml
EUR 425

Toll Like Receptor 2 (TLR2) Antibody

abx270107-200l 200 µl
EUR 300

Toll Like Receptor 2 (TLR2) Antibody

abx224269-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody

abx224396-100g 100 µg
EUR 362.5

ELISA kit for Mouse TLR2 (Toll Like Receptor 2)

ELK2666 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Toll Like Receptor 2 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Biotinylated

4-PAA663Mu01-Biotin
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Biotin.

Active Toll Like Receptor 2 (TLR2)

APA663Hu02 10ug
EUR 160

Active Toll Like Receptor 2 (TLR2)

APA663Hu04 10ug
EUR 160

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), APC-Cy7

4-PAA663Mu01-APC-Cy7
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Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with APC-Cy7.

Mouse Toll Like Receptor 2 (TLR2) Mini Samples ELISA Kit

MBS2087522-10x96StripWells 10x96-Strip-Wells
EUR 6900

Mouse Toll Like Receptor 2 (TLR2) Mini Samples ELISA Kit

MBS2087522-24StripWells 24-Strip-Wells
EUR 455

Mouse Toll Like Receptor 2 (TLR2) Mini Samples ELISA Kit

MBS2087522-48StripWells 48-Strip-Wells
EUR 705

Mouse Toll Like Receptor 2 (TLR2) Mini Samples ELISA Kit

MBS2087522-5x96StripWells 5x96-Strip-Wells
EUR 3865

Mouse Toll Like Receptor 2 (TLR2) Mini Samples ELISA Kit

MBS2087522-96StripWells 96-Strip-Wells
EUR 965

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit DIY Materials

MBS2088727-10x96Tests 10x96Tests
EUR 1800

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit DIY Materials

MBS2088727-10x96TestsMBS2089471SupportPack110x96Tests 10x96Tests+MBS2089471(SupportPack1,10x96Tests)
EUR 1910

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit DIY Materials

MBS2088727-5x96Tests 5x96Tests
EUR 1130

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit DIY Materials

MBS2088727-5x96TestsMBS2089471SupportPack15x96Tests 5x96Tests+MBS2089471(SupportPack1,5x96Tests)
EUR 1190

Toll Like Receptor 2 (TLR2) Antibody (PE)

20-abx270869
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  • 25 tests
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Toll Like Receptor 2 (TLR2) Antibody (PE)

abx270869-1ml 1 ml
EUR 687.5

Toll Like Receptor 2 (TLR2) Antibody (PE)

abx270869-200l 200 µl
EUR 575

Toll Like Receptor 2 (TLR2) Antibody (PE)

abx414263-200l 200 µl
EUR 487.5

Toll Like Receptor 2 (TLR2) Antibody (APC)

20-abx270637
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  • 25 tests
  • 50 tests
  • 100 tests
  • 200 tests
  • 500 tests

Toll Like Receptor 2 (TLR2) Antibody (APC)

abx270637-1ml 1 ml
EUR 800

Toll Like Receptor 2 (TLR2) Antibody (APC)

abx270637-200l 200 µl
EUR 662.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-20g 20 µg
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-50g 50 µg
EUR 250

Recombinant Toll Like Receptor 2 (TLR2)

MBS2029557-001mg 0.01mg
EUR 165

Recombinant Toll Like Receptor 2 (TLR2)

MBS2029557-005mg 0.05mg
EUR 285

Recombinant Toll Like Receptor 2 (TLR2)

MBS2029557-01mg 0.1mg
EUR 425

Recombinant Toll Like Receptor 2 (TLR2)

MBS2029557-02mg 0.2mg
EUR 515

Recombinant Toll Like Receptor 2 (TLR2)

MBS2029557-05mg 0.5mg
EUR 980

Recombinant Toll Like Receptor 2 (TLR2)

MBS2122676-001mg 0.01mg
EUR 155

Recombinant Toll Like Receptor 2 (TLR2)

MBS2122676-005mg 0.05mg
EUR 260

Recombinant Toll Like Receptor 2 (TLR2)

MBS2122676-01mg 0.1mg
EUR 375

Recombinant Toll Like Receptor 2 (TLR2)

MBS2122676-02mg 0.2mg
EUR 460

Recombinant Toll Like Receptor 2 (TLR2)

MBS2122676-05mg 0.5mg
EUR 860

Recombinant Toll Like Receptor 2 (TLR2)

MBS2012027-001mg 0.01mg
EUR 140

Recombinant Toll Like Receptor 2 (TLR2)

MBS2012027-005mg 0.05mg
EUR 235

Recombinant Toll Like Receptor 2 (TLR2)

MBS2012027-01mg 0.1mg
EUR 325

Recombinant Toll Like Receptor 2 (TLR2)

MBS2012027-02mg 0.2mg
EUR 400

Recombinant Toll Like Receptor 2 (TLR2)

MBS2012027-05mg 0.5mg
EUR 745

Recombinant Toll Like Receptor 2 (TLR2)

MBS2010927-001mg 0.01mg
EUR 165

Recombinant Toll Like Receptor 2 (TLR2)

MBS2010927-005mg 0.05mg
EUR 295

Recombinant Toll Like Receptor 2 (TLR2)

MBS2010927-01mg 0.1mg
EUR 440

Recombinant Toll Like Receptor 2 (TLR2)

MBS2010927-02mg 0.2mg
EUR 535

Recombinant Toll Like Receptor 2 (TLR2)

MBS2010927-05mg 0.5mg
EUR 1015

Recombinant Toll Like Receptor 2 (TLR2)

MBS2009386-001mg 0.01mg
EUR 140

Recombinant Toll Like Receptor 2 (TLR2)

MBS2009386-005mg 0.05mg
EUR 235

Recombinant Toll Like Receptor 2 (TLR2)

MBS2009386-01mg 0.1mg
EUR 325

Recombinant Toll Like Receptor 2 (TLR2)

MBS2009386-02mg 0.2mg
EUR 400

Recombinant Toll Like Receptor 2 (TLR2)

MBS2009386-05mg 0.5mg
EUR 745

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu01 10ug
EUR 120

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu01
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  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu02 10ug
EUR 120

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu02
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  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu03 10ug
EUR 140

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu04 10ug
EUR 122

Our results also indicate that HMGB-1 is set through the JNK signaling pathway Cx43, and Cx43 are involved in inflammation-mediated HMGB-1 in astrocytes. In vivo analysis supports the idea that HMGB-1-induced mechanical hypersensitivity associated with Cx43. Therefore, we conclude that HMGB-1-induced mechanical hypersensitivity pain occurs through modulation of astrocytic Cx43 through the TLR-4 / JNK signaling.