Toll–Like Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

Although vascular dysfunction is a key event in the development of diabetic complications, and abnormal pulse like receptor 4 (TLR4) may contribute to the pathophysiology of vascular disease, a direct link between TLR4 and function of blood vessels in the arterial diabetes remains poorly understood. Thus, to investigate whether pharmacological blockade of TLR4 affect blood vessel function in the superior mesenteric artery (SMA) of streptozotocin (STZ) -induced diabetic rats, SMA isolated from male Wistar rats were injected once with STZ (65 mg / kg, 27 – 34 weeks) treated with TAK-242 (10-6 M), TLR4 inhibitor, for about 1 d using organ culture techniques.

After incubation, functional and biochemical studies performed. In functional studies, treatment with TAK-242 increased by acetylcholine (ACh) induced relaxation of SMA diabetes in the intact condition. Sodium nitroprusside (SNP) induced relaxation was also increased in the group of TAK-242-treated compared to vehicle-treated group. Under the cyclooxygenase (COX) blockade by indomethacin (10-5 M), Ach-induced relaxation was similar in-vehicle group and TAK-242-treated.

Additionally, ACh-induced relaxation in the presence of a combination of nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine (L-NNA) (10-4 M) and indomethacin (10-5 M) were similar in the group vehicle-and TAK-242-treated. Productions of thromboxane (TX) B2 in the culture medium in the presence of ACh (10-5 M) was lower in the group of TAK-242-treated compared to vehicle-treated group.

These data show that the TAK-242 could improve endothelium-dependent relaxation by partially suppress TXA2 vasoconstrictor or increase NO signal. TLR4 inhibition may be a new therapeutic strategy to assist in the management of vascular complications associated with diabetes.

 <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em> Inhibitor TAK-2<em>4</em>2 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat
TollLike Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

high group mobility boxes-1 induces mechanical pain hypersensitivity through connexin astrocytic 4 3 through Tol – like receptor – < em> 4 / JNK signaling pathway

This study aimed to investigate the effect of box-1-high mobility group (HMGB-1) on the mechanical pain and hypersensitivity underlying mechanisms. Rat primary astrocytes were isolated and treated as specified. A CCK-8 assay was used to determine cytotoxicity and test gap junctional communication is done. Ethidium bromide (EtBr) uptake is used to evaluate the activity hemichannel primary astrocytes.

A rat model of neuropathic pain developed and foot withdrawal thresholds used to evaluate the sensitivity of its hind legs. RT-qPCR and Western blot was used to determine the mRNA and protein expression of the gene, respectively. ELISA was used to measure the release of inflammatory cytokines. Treatment with HMGB-1 increased the expression of both pulses like receptor-4 (TLR-4) and connexin 43 (Cx43) in rat primary astrocytes. HMGB-1 also promoted gap junctional communication between cells and function hemichannel.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-48Tests 48 Tests
EUR 511

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-96Tests 96 Tests
EUR 709

Human Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Hu-48Tests 48 Tests
EUR 478

Human Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Hu-96Tests 96 Tests
EUR 662

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-48Tests 48 Tests
EUR 511

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-96Tests 96 Tests
EUR 709

Human Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Hu-48T 48T
EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 2 (TLR2) in samples from serum, plasma, tissue homogenates, cell lysates, saliva, cell culture supernates or other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Hu-96T 96T
EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 2 (TLR2) in samples from serum, plasma, tissue homogenates, cell lysates, saliva, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Hu-48Tests 48 Tests
EUR 500

Human Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Hu-96Tests 96 Tests
EUR 692

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-48Tests 48 Tests
EUR 534

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-96Tests 96 Tests
EUR 742

Mouse Toll Like Receptor 2 (TLR2) Protein

20-abx167213
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu01
  • EUR 368.80
  • EUR 202.00
  • EUR 1108.00
  • EUR 436.00
  • EUR 772.00
  • EUR 310.00
  • EUR 2620.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu02
  • EUR 368.80
  • EUR 202.00
  • EUR 1108.00
  • EUR 436.00
  • EUR 772.00
  • EUR 310.00
  • EUR 2620.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Mu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Ra01
  • EUR 472.74
  • EUR 229.00
  • EUR 1497.76
  • EUR 565.92
  • EUR 1031.84
  • EUR 379.00
  • EUR 3594.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Toll Like Receptor 2 expressed in: E.coli

Human Toll-like receptor 2 (TLR2)

1-CSB-EP023601HU1
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Toll-like receptor 2(TLR2),partial expressed in E.coli

Toll-Like Receptor 2 (TLR2) Antibody

20-abx126707
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx129332
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll-Like Receptor 2 (TLR2) Antibody

20-abx110267
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll-Like Receptor 2 (TLR2) Antibody

20-abx123395
  • EUR 592.00
  • EUR 857.00
  • EUR 411.00
  • 100 ul
  • 200 ul
  • 50 ul

Toll-Like Receptor 2 (TLR2) Antibody

20-abx001983
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx102058
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102059
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102060
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102061
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102062
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll-Like Receptor 2 (TLR2) Antibody

abx147259-100ug 100 ug
EUR 439

Toll-Like Receptor 2 (TLR2) Antibody

abx147260-100ug 100 ug
EUR 439

Toll-Like Receptor 2 (TLR2) Antibody

20-abx137432
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug

Toll-Like Receptor 2 (TLR2) Antibody

abx011833-100ul 100 ul
EUR 411

Toll-Like Receptor 2 (TLR2) Antibody

abx027542-400ul 400 ul
EUR 523

Toll-Like Receptor 2 (TLR2) Antibody

abx027542-80l 80 µl
EUR 286

Toll-Like Receptor 2 (TLR2) Antibody

abx028479-400ul 400 ul
EUR 523

Toll-Like Receptor 2 (TLR2) Antibody

abx028479-80l 80 µl
EUR 286

Toll-Like Receptor 2 (Tlr2) Antibody

abx028480-400ul 400 ul
EUR 523

Toll-Like Receptor 2 (Tlr2) Antibody

abx028480-80l 80 µl
EUR 286

Toll Like Receptor 2 (TLR2) Antibody

20-abx270107
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody

20-abx212302
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212303
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212686
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212687
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx178628
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx174839
  • EUR 843.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Toll-Like Receptor 2 (Tlr2) Antibody

abx224269-100ug 100 ug
EUR 411

Toll-Like Receptor 2 (Tlr2) Antibody

abx224396-100ug 100 ug
EUR 411

Toll Like Receptor 2 (TLR2) Antibody

20-abx326823
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-10x96wellstestplate 10x96-wells test plate
EUR 4391.16
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x48wellstestplate 1x48-wells test plate
EUR 449.27
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x96wellstestplate 1x96-wells test plate
EUR 598.96
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-5x96wellstestplate 5x96-wells test plate
EUR 2395.32
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Mu
  • EUR 4442.00
  • EUR 2346.00
  • EUR 599.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse)

4-PAA663Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2)

Mouse Toll-like receptor 2(TLR2)ELISA Kit    

GA-E0414MS-48T 48T
EUR 336

Mouse Toll-like receptor 2(TLR2)ELISA Kit    

GA-E0414MS-96T 96T
EUR 534

Mouse Tlr2/ Toll-like receptor 2 ELISA Kit

E1480Mo 1 Kit
EUR 571

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

abx575343-96tests 96 tests
EUR 668

Mouse Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491847
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Toll-like Receptor 2 (TLR2) ELISA Kit

abx254557-96tests 96 tests
EUR 754

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

20-abx154784
  • EUR 6642.00
  • EUR 3542.00
  • EUR 825.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Toll Like Receptor 2(TLR2)ELISA Kit

QY-E21479 96T
EUR 361

Mouse TLR2(Toll-like receptor 2) ELISA Kit

EM0182 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Mouse Toll- like receptor 2, Tlr2 ELISA KIT

ELI-02327m 96 Tests
EUR 865

TLR2 Toll Like Receptor 2 MouseRecombinant Protein

PROTQ9QUN7 Regular: 5ug
EUR 317
Description: TLR2 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 805 amino acids (25-587a.a.) and having a molecular mass of 90.7kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).;TLR2 is expressed with a 239 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Toll Like Receptor 2 (TLR2) Antibody Pair

20-abx370287
  • EUR 1288.00
  • EUR 843.00
  • 10 × 96 tests
  • 5 × 96 tests

Toll Like Receptor 2 (TLR2) Antibody Pair

20-abx370561
  • EUR 1622.00
  • EUR 1038.00
  • 10 × 96 tests
  • 5 × 96 tests

Human Toll Like Receptor 2 (TLR2) Protein

20-abx069358
  • EUR 523.00
  • EUR 244.00
  • EUR 1497.00
  • EUR 606.00
  • EUR 384.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 2 (TLR2) Protein

20-abx069359
  • EUR 662.00
  • EUR 272.00
  • EUR 2026.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Toll Like Receptor 2 (TLR2) Protein

20-abx069360
  • EUR 523.00
  • EUR 244.00
  • EUR 1497.00
  • EUR 606.00
  • EUR 384.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (FITC)

20-abx270405
  • EUR 523.00
  • EUR 606.00
  • EUR 300.00
  • EUR 940.00
  • EUR 384.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (APC)

20-abx270637
  • EUR 704.00
  • EUR 829.00
  • EUR 370.00
  • EUR 1330.00
  • EUR 495.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (PE)

20-abx270869
  • EUR 606.00
  • EUR 718.00
  • EUR 328.00
  • EUR 1135.00
  • EUR 439.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

20-abx274516
  • EUR 342.00
  • EUR 203.00
  • EUR 857.00
  • EUR 439.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

20-abx272025
  • EUR 425.00
  • EUR 230.00
  • EUR 1191.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (FITC)

20-abx273768
  • EUR 453.00
  • EUR 244.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), APC

4-PAA663Mu01-APC
  • EUR 329.00
  • EUR 3041.00
  • EUR 854.00
  • EUR 416.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with APC.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Biotinylated

4-PAA663Mu01-Biotin
  • EUR 299.00
  • EUR 2288.00
  • EUR 684.00
  • EUR 363.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Biotin.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Cy3

4-PAA663Mu01-Cy3
  • EUR 397.00
  • EUR 4013.00
  • EUR 1097.00
  • EUR 513.00
  • EUR 241.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Cy3.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), FITC

4-PAA663Mu01-FITC
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with FITC.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), HRP

4-PAA663Mu01-HRP
  • EUR 302.00
  • EUR 2652.00
  • EUR 756.00
  • EUR 377.00
  • EUR 200.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with HRP.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), PE

4-PAA663Mu01-PE
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with PE.

ELISA kit for Mouse TLR2 (Toll Like Receptor 2)

ELK2666 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Toll Like Receptor 2 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

for Toll Like Receptor 2 (TLR2)ELISA kit

SEA663Bo-10x96wellstestplate 10x96-wells test plate
EUR 5098.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Toll Like Receptor 2 (TLR2) in Saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Toll Like Receptor 2 (TLR2)ELISA kit

SEA663Bo-1x48wellstestplate 1x48-wells test plate
EUR 507.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Toll Like Receptor 2 (TLR2) in Saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Toll Like Receptor 2 (TLR2)ELISA kit

SEA663Bo-1x96wellstestplate 1x96-wells test plate
EUR 682.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Toll Like Receptor 2 (TLR2) in Saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Toll Like Receptor 2 (TLR2)ELISA kit

SEA663Bo-5x96wellstestplate 5x96-wells test plate
EUR 2769.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Toll Like Receptor 2 (TLR2) in Saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

ELISA Kit for Toll Like Receptor 2 (TLR2)

4-SEA663Bo
  • EUR 5149.00
  • EUR 2720.00
  • EUR 683.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Toll Like Receptor 2 (TLR2) in samples from Saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Hu-10x96wellstestplate 10x96-wells test plate
EUR 3409.41
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 2 (TLR2) in saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Hu-1x48wellstestplate 1x48-wells test plate
EUR 368.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 2 (TLR2) in saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Hu-1x96wellstestplate 1x96-wells test plate
EUR 483.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 2 (TLR2) in saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Hu-5x96wellstestplate 5x96-wells test plate
EUR 1875.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 2 (TLR2) in saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Hu
  • EUR 3460.00
  • EUR 1826.00
  • EUR 484.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 2 (TLR2) in samples from saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Our results also indicate that HMGB-1 is set through the JNK signaling pathway Cx43, and Cx43 are involved in inflammation-mediated HMGB-1 in astrocytes. In vivo analysis supports the idea that HMGB-1-induced mechanical hypersensitivity associated with Cx43. Therefore, we conclude that HMGB-1-induced mechanical hypersensitivity pain occurs through modulation of astrocytic Cx43 through the TLR-4 / JNK signaling.