Toll–Like Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

Although vascular dysfunction is a key event in the development of diabetic complications, and abnormal pulse like receptor 4 (TLR4) may contribute to the pathophysiology of vascular disease, a direct link between TLR4 and function of blood vessels in the arterial diabetes remains poorly understood. Thus, to investigate whether pharmacological blockade of TLR4 affect blood vessel function in the superior mesenteric artery (SMA) of streptozotocin (STZ) -induced diabetic rats, SMA isolated from male Wistar rats were injected once with STZ (65 mg / kg, 27 – 34 weeks) treated with TAK-242 (10-6 M), TLR4 inhibitor, for about 1 d using organ culture techniques.

After incubation, functional and biochemical studies performed. In functional studies, treatment with TAK-242 increased by acetylcholine (ACh) induced relaxation of SMA diabetes in the intact condition. Sodium nitroprusside (SNP) induced relaxation was also increased in the group of TAK-242-treated compared to vehicle-treated group. Under the cyclooxygenase (COX) blockade by indomethacin (10-5 M), Ach-induced relaxation was similar in-vehicle group and TAK-242-treated.

Additionally, ACh-induced relaxation in the presence of a combination of nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine (L-NNA) (10-4 M) and indomethacin (10-5 M) were similar in the group vehicle-and TAK-242-treated. Productions of thromboxane (TX) B2 in the culture medium in the presence of ACh (10-5 M) was lower in the group of TAK-242-treated compared to vehicle-treated group.

These data show that the TAK-242 could improve endothelium-dependent relaxation by partially suppress TXA2 vasoconstrictor or increase NO signal. TLR4 inhibition may be a new therapeutic strategy to assist in the management of vascular complications associated with diabetes.

 <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em> Inhibitor TAK-2<em>4</em>2 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat
TollLike Receptor 4 Inhibitor TAK-242 Augments Acetylcholine-Induced Relaxation in Superior Mesenteric Arteries of the Streptozotocin-Induced Diabetic Rat

high group mobility boxes-1 induces mechanical pain hypersensitivity through connexin astrocytic 4 3 through Tol – like receptor – < em> 4 / JNK signaling pathway

This study aimed to investigate the effect of box-1-high mobility group (HMGB-1) on the mechanical pain and hypersensitivity underlying mechanisms. Rat primary astrocytes were isolated and treated as specified. A CCK-8 assay was used to determine cytotoxicity and test gap junctional communication is done. Ethidium bromide (EtBr) uptake is used to evaluate the activity hemichannel primary astrocytes.

A rat model of neuropathic pain developed and foot withdrawal thresholds used to evaluate the sensitivity of its hind legs. RT-qPCR and Western blot was used to determine the mRNA and protein expression of the gene, respectively. ELISA was used to measure the release of inflammatory cytokines. Treatment with HMGB-1 increased the expression of both pulses like receptor-4 (TLR-4) and connexin 43 (Cx43) in rat primary astrocytes. HMGB-1 also promoted gap junctional communication between cells and function hemichannel.

Mouse Toll Like Receptor 2 (TLR2) Protein

abx680018-100g 100 µg
EUR 225

Mouse Toll Like Receptor 2 (TLR2) Protein

abx680018-200g 200 µg
EUR 325

Mouse Toll Like Receptor 2 (TLR2) Protein

abx692566-100g 100 µg
EUR 837.5

Mouse Toll Like Receptor 2 (TLR2) Protein

abx692566-1mg 1 mg Ask for price

Mouse Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491847
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu 96T
EUR 432
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu-48T 48T
EUR 586.8
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Mu-96T 96T
EUR 762
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-48T 48T
EUR 514.08

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-5x96T 5x96T
EUR 3488.4

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07748-96T 96T
EUR 734.4

Mouse Toll- like receptor 2, Tlr2 ELISA KIT

ELI-02327m 96 Tests
EUR 1038

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-48T 48T
EUR 350.42

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-5x96T 5x96T
EUR 2377.85

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48859-96T 96T
EUR 500.6

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

DL-TLR2-Mu 96T
EUR 412
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

EK16960 96Т
EUR 768

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

abx575343-96tests 96 tests
EUR 801.6

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

20-abx154784
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-48T 48T
EUR 422.3
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-48Tests 48 Tests
EUR 586.8

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-96T 96T
EUR 603.3
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Mu-96Tests 96 Tests
EUR 812.4

Mouse Toll Like Receptor 2(TLR2)ELISA Kit

QY-E21479 96T
EUR 433.2

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-10x96wellstestplate 10x96-wells test plate
EUR 5269.39
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x48wellstestplate 1x48-wells test plate
EUR 539.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-1x96wellstestplate 1x96-wells test plate
EUR 718.75
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Mu-5x96wellstestplate 5x96-wells test plate
EUR 2874.38
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Toll Like Receptor 2 (TLR2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Mu
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

SL0779Mo -
EUR 528

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-48T 48T
EUR 443.42
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-48Tests 48 Tests
EUR 613.2

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-96T 96T
EUR 633.47
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Mu-96Tests 96 Tests
EUR 850.8

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse)

4-PAA663Mu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2)

Mouse Toll Like Receptor 2, TLR2 GENLISA ELISA    

KLM0401 1 x 96 wells
EUR 341

Mouse TLR2(Toll Like Receptor 2) ELISA Kit

ELK2666-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TLR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TLR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse TLR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse TLR2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse TLR2(Toll Like Receptor 2) ELISA Kit

ELK2666-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TLR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TLR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse TLR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse TLR2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Toll Like Receptor 2 (TLR2) Antibody

20-abx326823
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx270107
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody

20-abx102058
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102059
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102060
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102061
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102062
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx129332
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx212302
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212303
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212686
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212687
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx174839
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx178628
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Toll Like Receptor 2 (TLR2) Antibody

abx001983-100l 100 µl
EUR 400

Toll Like Receptor 2 (TLR2) Antibody

abx001983-20l 20 µl
EUR 175

Toll Like Receptor 2 (TLR2) Antibody

abx001983-50l 50 µl
EUR 275

Toll Like Receptor 2 (TLR2) Antibody

abx011833-100g 100 µg Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx011833-10g 10 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody

abx011833-200g 200 µg Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx224396-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody

abx270107-1ml 1 ml
EUR 425

Toll Like Receptor 2 (TLR2) Antibody

abx270107-200l 200 µl
EUR 300

Toll Like Receptor 2 (TLR2) Antibody

abx129332-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

abx129332-1ml 1 ml
EUR 687.5

Toll Like Receptor 2 (TLR2) Antibody

abx129332-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx110267-100l 100 µl
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody

abx137432-100tests 100 tests
EUR 225

Toll Like Receptor 2 (TLR2) Antibody

abx102058-100l 100 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx102058-1ml 1 ml
EUR 675

Toll Like Receptor 2 (TLR2) Antibody

abx102058-200l 200 µl
EUR 312.5

Toll Like Receptor 2 (TLR2) Antibody

abx102059-100l 100 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx102059-1ml 1 ml
EUR 675

Toll Like Receptor 2 (TLR2) Antibody

abx102059-200l 200 µl
EUR 312.5

Toll Like Receptor 2 (TLR2) Antibody

abx102060-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

abx102060-1ml 1 ml
EUR 712.5

Toll Like Receptor 2 (TLR2) Antibody

abx102060-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx102061-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

abx102061-1ml 1 ml
EUR 712.5

Toll Like Receptor 2 (TLR2) Antibody

abx102061-200l 200 µl
EUR 325

Toll Like Receptor 2 (TLR2) Antibody

abx102062-100l 100 µl
EUR 262.5

Toll Like Receptor 2 (TLR2) Antibody

abx102062-1ml 1 ml
EUR 725

Toll Like Receptor 2 (TLR2) Antibody

abx102062-200l 200 µl
EUR 337.5

Toll Like Receptor 2 (TLR2) Antibody

abx224269-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody

abx239892-100l 100 µl Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx239892-50l 50 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx147259-1096tests 10 × 96 tests Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx147259-596tests 5 × 96 tests Ask for price

Toll Like Receptor 2 (TLR2) Antibody

abx147259-96tests 96 tests
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx027542-400l 400 µl
EUR 518.75

Toll Like Receptor 2 (TLR2) Antibody

abx028479-400l 400 µl
EUR 518.75

Toll Like Receptor 2 (TLR2) Antibody

abx028480-400l 400 µl
EUR 525

Toll Like Receptor 2 (TLR2) Antibody

abx174839-25g 25 g
EUR 775

Toll Like Receptor 2 (TLR2) Antibody

abx212302-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx212302-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx212303-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx212303-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx212686-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx212686-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx212687-100l 100 µl
EUR 350

Toll Like Receptor 2 (TLR2) Antibody

abx212687-50l 50 µl
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx326823-100g 100 µg
EUR 250

Toll Like Receptor 2 (TLR2) Antibody

abx326823-50g 50 µg
EUR 187.5

Toll Like Receptor 2 (TLR2) Antibody

abx412013-100g 100 µg
EUR 462.5

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), PE

4-PAA663Mu01-PE
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with PE.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), APC

4-PAA663Mu01-APC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with APC.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Cy3

4-PAA663Mu01-Cy3
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Cy3.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), HRP

4-PAA663Mu01-HRP
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with HRP.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), FITC

4-PAA663Mu01-FITC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with FITC.

Active Toll Like Receptor 2 (TLR2)

APA663Hu02 10ug
EUR 160

Active Toll Like Receptor 2 (TLR2)

APA663Hu04 10ug
EUR 160

ELISA kit for Mouse TLR2 (Toll Like Receptor 2)

ELK2666 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Toll Like Receptor 2 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Toll Like Receptor 2 (TLR2) Antibody (PE)

20-abx270869
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (PE)

abx270869-1ml 1 ml
EUR 687.5

Toll Like Receptor 2 (TLR2) Antibody (PE)

abx270869-200l 200 µl
EUR 575

Toll Like Receptor 2 (TLR2) Antibody (PE)

abx414263-200l 200 µl
EUR 487.5

Recombinant Toll Like Receptor 2 (TLR2)

RPU44066-100ug 100ug
EUR 369.6

Recombinant Toll Like Receptor 2 (TLR2)

RPU44066-1mg 1mg
EUR 1638

Recombinant Toll Like Receptor 2 (TLR2)

RPU44066-50ug 50ug
EUR 297

Recombinant Toll Like Receptor 2 (TLR2)

RPU44067-100ug 100ug
EUR 512.6

Recombinant Toll Like Receptor 2 (TLR2)

RPU44067-1mg 1mg
EUR 2271.1

Recombinant Toll Like Receptor 2 (TLR2)

RPU44067-50ug 50ug
EUR 411.4

Recombinant Toll Like Receptor 2 (TLR2)

RPU44068-100ug 100ug
EUR 369.6

Recombinant Toll Like Receptor 2 (TLR2)

RPU44068-1mg 1mg
EUR 1638

Recombinant Toll Like Receptor 2 (TLR2)

RPU44068-50ug 50ug
EUR 297

Recombinant Toll Like Receptor 2 (TLR2)

RPU51497-100ug 100ug
EUR 492.8

Recombinant Toll Like Receptor 2 (TLR2)

RPU51497-1mg 1mg
EUR 2184

Recombinant Toll Like Receptor 2 (TLR2)

RPU51497-50ug 50ug
EUR 396

Recombinant Toll Like Receptor 2 (TLR2)

RPU56784-100ug 100ug
EUR 470.4

Recombinant Toll Like Receptor 2 (TLR2)

RPU56784-1mg 1mg
EUR 2184

Recombinant Toll Like Receptor 2 (TLR2)

RPU56784-50ug 50ug
EUR 385

Recombinant Toll Like Receptor 2 (TLR2)

RPU56785-100ug 100ug
EUR 470.4

Recombinant Toll Like Receptor 2 (TLR2)

RPU56785-1mg 1mg
EUR 2184

Recombinant Toll Like Receptor 2 (TLR2)

RPU56785-50ug 50ug
EUR 385

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu01 10ug
EUR 120

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu02 10ug
EUR 120

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Hu02
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu03 10ug
EUR 140

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Hu04 10ug
EUR 122

Recombinant Toll Like Receptor 2 (TLR2)

RPA663Mu01 10ug
EUR 160

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Mu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Toll Like Receptor 2 expressed in: E.coli

Recombinant Toll Like Receptor 2 (TLR2)

4-RPA663Ra01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Toll Like Receptor 2 expressed in: E.coli

Toll Like Receptor 2 (TLR2) Antibody (APC)

20-abx270637
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (APC)

abx270637-1ml 1 ml
EUR 800

Toll Like Receptor 2 (TLR2) Antibody (APC)

abx270637-200l 200 µl
EUR 662.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-20g 20 µg
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody (HRP)

abx108812-50g 50 µg
EUR 250

Toll Like Receptor 2 (TLR2) Antibody Pair

20-abx370287
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests

Toll Like Receptor 2 (TLR2) Antibody Pair

20-abx370561
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests

Toll Like Receptor 2 (TLR2) Antibody (FITC)

20-abx270405
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Toll Like Receptor 2 (TLR2) Antibody (FITC)

20-abx273768
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx270405-1ml 1 ml
EUR 575

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx270405-200l 200 µl
EUR 475

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx273768-25mg 25 mg
EUR 950

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx273768-5mg 5 mg
EUR 400

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx107392-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx107392-20g 20 µg
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx107392-50g 50 µg
EUR 250

Toll Like Receptor 2 (TLR2) Antibody Pair

abx370287-100g 100 µg
EUR 975

Toll Like Receptor 2 (TLR2) Antibody Pair

abx370561-100g 100 µg
EUR 2200

Toll Like Receptor 2 (TLR2) Antibody Pair

abx370561-50g 50 µg
EUR 1350

Toll Like Receptor 2 (TLR2) Antibody (FITC)

abx414262-200l 200 µl
EUR 400

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

20-abx274516
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

20-abx272025
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx272025-1ml 1 ml
EUR 737.5

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx272025-200l 200 µl
EUR 337.5

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx274516-100tests 100 tests
EUR 275

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx105977-100g 100 µg
EUR 362.5

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx105977-20g 20 µg
EUR 162.5

Toll Like Receptor 2 (TLR2) Antibody (Biotin)

abx105977-50g 50 µg
EUR 250

TLR2 Toll Like Receptor 2 MouseRecombinant Protein

PROTQ9QUN7 Regular: 5ug
EUR 380.4
Description: TLR2 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 805 amino acids (25-587a.a.) and having a molecular mass of 90.7kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).;TLR2 is expressed with a 239 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), Biotinylated

4-PAA663Mu01-Biotin
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with Biotin.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Mouse), APC-Cy7

4-PAA663Mu01-APC-Cy7
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Toll Like Receptor 2 (TLR2). This antibody is labeled with APC-Cy7.

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27419-100ul 100ul
EUR 229.4

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27419-200ul 200ul
EUR 287.3

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27420-100ul 100ul
EUR 217.9

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27420-200ul 200ul
EUR 272.2

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27421-100ul 100ul
EUR 212.2

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27421-200ul 200ul
EUR 265.4

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27422-100ul 100ul
EUR 212.2

Toll Like Receptor 2 (TLR2) Polyclonal Antibody

CAU27422-200ul 200ul
EUR 265.4

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU30055-100ul 100ul
EUR 225.6

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU30055-200ul 200ul
EUR 282.2

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU30234-100ul 100ul
EUR 228.5

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU30234-200ul 200ul
EUR 285.6

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU29284-100ul 100ul
EUR 225.6

Toll Like Receptor 2 (TLR2) Monoclonal Antibody

CAU29284-200ul 200ul
EUR 282.2

Rat Toll Like Receptor 2 (TLR2) Protein

20-abx069359
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 2 (TLR2) Protein

abx069359-25mg 25 mg
EUR 387.5

Rat Toll Like Receptor 2 (TLR2) Protein

abx069359-5mg 5 mg
EUR 212.5

Our results also indicate that HMGB-1 is set through the JNK signaling pathway Cx43, and Cx43 are involved in inflammation-mediated HMGB-1 in astrocytes. In vivo analysis supports the idea that HMGB-1-induced mechanical hypersensitivity associated with Cx43. Therefore, we conclude that HMGB-1-induced mechanical hypersensitivity pain occurs through modulation of astrocytic Cx43 through the TLR-4 / JNK signaling.