Low Maternal Dietary Intake of Choline Regulates TollLike Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

Low Maternal Dietary Intake of Choline Regulates Toll-Like Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

Scope: Choline is an essential nutrient and a primary food source of vital methyl groups for brain development. The low choline (LC) in the maternal regime during pregnancy modifies neurogenesis in the fetal brain and leads to low cognitive performance. However, the main signs sensitive to the supply of maternal cholines during the development of the neural production cell (NPC) and epigenetic mechanisms by which the availability of choline regulates the expression of genes are unclear.

Methods and Results: The transgenic mice of Nestin-CFPNU-CFPNUT timed have been fed either a control regime or an LC system during E11-17. Changes in gene expression The e17 Trolling NPCs have been identified by NRA sequencing. An LC maternal regime has increased dramatically the TLR4 transcription, causing premature neuronal differentiation and improved activation of ethanol-induced inflammor induced by ethanol. No change in methylation of DNA to the TLR4 gene promoter region has been detected; However, a 70% decrease in H3K27ME3 was observed in the NPC treated with LC. The inhibition of the EZH2 decreased the H3K27me levels and an increased TLR4 expression. Conversely, the application of catalytically inactive CAS9 with EZH2 to increase H3K27me3 to the TLR4 promoter caused a reduced expression of TLR4.

Conclusion: These data reveal an epigenetic mechanism for the effect of the availability of maternal choline on brain development, suggesting likely intervention for neurodevelopmental disease. This article is protected by copyright. All rights reserved.

<em> toll </ em> – <em> like </ em> <em> </ em> <em> 4 </ em> activates the path of inflammasome of the NLRP3 and a periodontal inflammation by inhibiting the Expression BMI-1

The overproduction of pro-inflammatory cytokines in the elderly, which is called inflammation, leads to the deterioration of periodontitis. The 4 (TLR4) toll receiver 4 (TLR4) plays a role in the regulation of cellular senescence and its expression increases with age. However, limited research on molecular mechanisms underlying the appearance of periodontal inflammation and interaction between TLR4 and inflammation.

In the present study, wild-type and TLR4 knock-knock mice were used to investigate the activation of the TLR4 channel in the periodontitis of the mouse and the expression of the nucleotide bonding receptor and oligomerization receptor Type 3 (NLRP3) Inflammasome, an upstream immune control point during the development of inflammation. The activation of TLR4 in a mouse periodontitis model has improved the expression of a secret phenotype (SAP) associated with senescence, which has stimulated the inflammation process. Conversely, the TLR4 activation has reduced the expression of the leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia 1 (BMI-1) and has promoted the initiation of NLRP3 inflammor, both of which are Saem regulators.

Gingival Fibroblast Treatment with BMI-1 Inhibitor PTC209, TLR4 has been shown to activate the NLRP3 channel and the inflammation process by deleting BMI-1. In addition, there was a significant reduction in the expression of the BMI-1 expression in gingiva patients with periodontitis compared to healthy controls. In conclusion, this study demonstrated that TLR4 acted by inhibiting BMI-1 to improve the lane of NLRP3 and SAP factors. This reaction waterfall can contribute to the periodontium senescence. The family of toll receptors (TLR) is composed of essential receptors responsible for the recognition of diagrams in innate immunity, making it the essential proteins involved in the detection of pathogens and by providing immune responses. The most studied member of this family, TLR4, was the focus of attention regarding its contributory role in many inflammatory diseases, including the sepsi shock and asthma. In particular, assembly evidence has proved that this receiver is aberrantly expressed on tumor cells and tumor microenvironment in a wide range of cancer types and is strongly associated with the initiation of tumorigenesis as well as the Progression of tumor and drug resistance.

 

 Low Maternal Dietary Intake of Choline Regulates <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em> Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells
Low Maternal Dietary Intake of Choline Regulates TollLike Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

<em> toll </ em> – <em> like </ em> <em> </ em> <em> 4 </ em> regulates intestinal fibrosis via cytokine expression and epithelial-mesenchymatory transition

The intestinal fibrosis induced by chronic and recurrent colitis, which is exacerbated by intestinal stenosis, stenosis and obstruction, is difficult to treat. The 4 (TLR4) toll receiver stimulates innate immunity and acquired in response to specific microbial components, but the role of TLR4 in intestinal fibrosis is largely unknown. We have examined its role in intestinal fibrosis using not only a model of murine fibrosis, but also human myofibroblasts and intestinal epithelial cells. Colon fibrosis has been induced in TLR4 deficient mice (TLR4 – / -) and its wild-type counterparts with 3% dextran sulphate. The absence of a TLR4 gene has mitigated chronic inflammation and infiltration of colic macrophages; Intestinal fibrosis and collagen deposition have been removed. In addition, the production of tumor necrosis factor-α, interleukin-12P40 and the transformant growth factor – β has been reduced in deficient macrophages of TLR4.

 

The TLR4 was silenced in CCD-18CO cells with a small interfering RNA (SIRNA) and the metalloproteinase-1 matrix, metalloproteinase tissue inhibitor and the collagenated α1 expression was evaluated. The role of TLR4 in the transition of epithelium-mesenchymates (EMT) was evaluated in HCT116 cells. Removal of SIRNAS TLR4 transcription affected myofibroblast activity, collagen synthesis and EMT in the human line of human cancer. Thus, we suggest that TLR4 can be an essential mediator in inflammation and intestinal chronic fibrosis, indicating that TLR4 signaling is a potential therapeutic target for intestinal fibrosis.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

20-abx128776
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

20-abx313314
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

abx236948-100ug 100 ug
EUR 577.2

Recombinant Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

4-RPB295Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Protein Tyrosine Phosphatase Receptor Type S expressed in: E.coli

Recombinant Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

4-RPB295Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Protein Tyrosine Phosphatase Receptor Type S expressed in: E.coli

Protein tyrosine phosphatase receptor-type S (PTPRS) polyclonal antibody

ABP-PAB-11050 100 ug Ask for price

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (HRP)

20-abx313315
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (FITC)

20-abx313316
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (Biotin)

20-abx313317
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (Biotin)

20-abx274229
  • EUR 543.60
  • EUR 292.80
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (FITC)

20-abx274614
  • EUR 560.40
  • EUR 292.80
  • EUR 1663.20
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Protein

20-abx068778
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Protein

20-abx167990
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human)

4-PAB295Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

DLR-PTPRS-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

DLR-PTPRS-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

20-abx152898
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) CLIA Kit

20-abx492605
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RD-PTPRS-Hu-48Tests 48 Tests
EUR 600

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RD-PTPRS-Hu-96Tests 96 Tests
EUR 830.4

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RDR-PTPRS-Hu-48Tests 48 Tests
EUR 626.4

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RDR-PTPRS-Hu-96Tests 96 Tests
EUR 868.8

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

4-SEB295Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Protein Tyrosine Phosphatase Receptor Type S ELISA Kit (PTPRS)

RK02166 96 Tests
EUR 625.2

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), APC

4-PAB295Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), Biotinylated

4-PAB295Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Biotin.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), Cy3

4-PAB295Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Cy3.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), FITC

4-PAB295Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with FITC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), HRP

4-PAB295Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with HRP.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), PE

4-PAB295Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with PE.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat)

4-PAB295Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

Receptor-type tyrosine-protein phosphatase zeta Antibody

20-abx109367
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase zeta Antibody

20-abx109368
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase R Antibody

20-abx110169
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase, Receptor Type, A Antibody

20-abx114876
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, E Antibody

20-abx114878
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, J Antibody

20-abx114881
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, M Antibody

20-abx114882
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, N Antibody

20-abx114883
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, R Antibody

20-abx114884
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), APC-Cy7

4-PAB295Hu01-APC-Cy7
  • EUR 656.40
  • EUR 7327.20
  • EUR 1948.80
  • EUR 872.40
  • EUR 372.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC-Cy7.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), APC

4-PAB295Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB295Mu01-Biotin
  • EUR 368.40
  • EUR 2888.40
  • EUR 856.80
  • EUR 450.00
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Biotin.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB295Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Cy3.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB295Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with FITC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB295Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with HRP.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), PE

4-PAB295Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with PE.

ELISA kit for Human PTPRS (Protein Tyrosine Phosphatase Receptor Type S)

ELK4856 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Protein Tyrosine Phosphatase Receptor Type S from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-100

AR09-P0014-100 100ug
EUR 1665.6

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-25

AR09-P0014-25 25ug
EUR 633.6

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-50

AR09-P0014-50 50ug
EUR 978

Receptor-type tyrosine-protein phosphatase R Antibody (HRP)

20-abx108705
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx104375
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104376
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104377
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104378
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104379
  • EUR 393.60
  • EUR 978.00
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx104380
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody

20-abx104381
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx104382
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase R Antibody (FITC)

20-abx107285
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

20-abx159666
  • EUR 326.40
  • EUR 276.00
  • 100 ug
  • 50 ug

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159667-100ul 100 ul
EUR 427.2

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159668-100ul 100 ul
EUR 427.2

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159669-100ul 100 ul
EUR 427.2

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159670-100ul 100 ul
EUR 427.2

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159671-100ul 100 ul
EUR 526.8

Receptor-Type Tyrosine-Protein Phosphatase C (PTPRC) Antibody

abx159672-100ul 100 ul
EUR 427.2

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody

20-abx174283
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx174284
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) Antibody

20-abx174285
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx149090
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

abx122351-100ug 100 ug
EUR 469.2

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx122352-100ug 100 ug
EUR 469.2

Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) Antibody

20-abx124253
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx124267
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx134009
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx134013
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx136077
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

20-abx136151
  • EUR 594.00
  • EUR 427.20
  • 100 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

20-abx137094
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

20-abx137491
  • EUR 844.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 20 ug
  • 5 ug

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx139820-01mg 0.1 mg
EUR 427.2

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx139823-01mg 0.1 mg
EUR 427.2

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx139824-01mg 0.1 mg
EUR 427.2

Receptor-Type Tyrosine-Protein Phosphatase Eta (CD148) Antibody

abx139844-01mg 0.1 mg
EUR 427.2

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx140074-01mg 0.1 mg
EUR 343.2

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx117211-100ug 100 ug
EUR 560.4

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx130068
  • EUR 376.80
  • EUR 159.60
  • EUR 994.80
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx130337
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx130342
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx131177
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx131178
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx131180
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx131512
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx131513
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx131514
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type E (PTPRE) Antibody

20-abx131515
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type F (PTPRF) Antibody

20-abx131516
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type U (PTPRU) Antibody

20-abx131517
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Antibody

20-abx131518
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Antibody

20-abx131519
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Antibody

20-abx131546
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx126438
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx126439
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx126440
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

20-abx127022
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody

20-abx128236
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx128746
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) Antibody

20-abx129111
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx129661
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx129751
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Antibody

20-abx129825
  • EUR 510.00
  • EUR 142.80
  • EUR 184.80
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 15 ug
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase, Non-Receptor Type 11 Antibody

20-abx114867
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 14 Antibody

20-abx114868
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 2 Antibody

20-abx114870
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 7 Antibody

20-abx114875
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx114886
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type U (PTPRU) Antibody

20-abx006232
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

20-abx006439
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Antibody

20-abx006633
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Antibody

20-abx006780
  • EUR 493.20
  • EUR 126.00
  • EUR 710.40
  • EUR 218.40
  • 100 ul
  • 10 ul
  • 200 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx006819
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx000698
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx001610
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

20-abx001727
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx002368
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx014804
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx014805
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx016120-100ug 100 ug
EUR 493.2

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx021437-02mg 0.2 mg
EUR 577.2

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx021440-1mg 1 mg
EUR 1161.6

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

abx010527-100ul 100 ul
EUR 493.2

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx026402-400ul 400 ul
EUR 627.6

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx026402-80l 80 µl
EUR 343.2

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx028034-400ul 400 ul
EUR 627.6

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx028034-80l 80 µl
EUR 343.2

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

abx028113-400ul 400 ul
EUR 627.6

Patients with type-2 diabetes mellitus (T2DM) have a low-quality chronic inflammation induced by activating the innate immune system. The toll receiver (TLR) 4 is a pattern recognition receiver that plays a vital role in activating the innate immune system. The results of the animal studies and the computer simulation computer have shown that the targeting of the TLR4 to block the TLR4-Nuclear Factor-Kappa B (NF-KB) route reduces the inflammatory response and the complications associated with T2DM . As a result, TLR4 targeted therapy has general prospects. Here we examined the role of TLR4 in inflammation during chronic hyperglycemia of T2DM and its therapeutic perspectives.

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