Low Maternal Dietary Intake of Choline Regulates TollLike Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

Low Maternal Dietary Intake of Choline Regulates Toll-Like Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

Scope: Choline is an essential nutrient and a primary food source of vital methyl groups for brain development. The low choline (LC) in the maternal regime during pregnancy modifies neurogenesis in the fetal brain and leads to low cognitive performance. However, the main signs sensitive to the supply of maternal cholines during the development of the neural production cell (NPC) and epigenetic mechanisms by which the availability of choline regulates the expression of genes are unclear.

Methods and Results: The transgenic mice of Nestin-CFPNU-CFPNUT timed have been fed either a control regime or an LC system during E11-17. Changes in gene expression The e17 Trolling NPCs have been identified by NRA sequencing. An LC maternal regime has increased dramatically the TLR4 transcription, causing premature neuronal differentiation and improved activation of ethanol-induced inflammor induced by ethanol. No change in methylation of DNA to the TLR4 gene promoter region has been detected; However, a 70% decrease in H3K27ME3 was observed in the NPC treated with LC. The inhibition of the EZH2 decreased the H3K27me levels and an increased TLR4 expression. Conversely, the application of catalytically inactive CAS9 with EZH2 to increase H3K27me3 to the TLR4 promoter caused a reduced expression of TLR4.

Conclusion: These data reveal an epigenetic mechanism for the effect of the availability of maternal choline on brain development, suggesting likely intervention for neurodevelopmental disease. This article is protected by copyright. All rights reserved.

<em> toll </ em> – <em> like </ em> <em> </ em> <em> 4 </ em> activates the path of inflammasome of the NLRP3 and a periodontal inflammation by inhibiting the Expression BMI-1

The overproduction of pro-inflammatory cytokines in the elderly, which is called inflammation, leads to the deterioration of periodontitis. The 4 (TLR4) toll receiver 4 (TLR4) plays a role in the regulation of cellular senescence and its expression increases with age. However, limited research on molecular mechanisms underlying the appearance of periodontal inflammation and interaction between TLR4 and inflammation.

In the present study, wild-type and TLR4 knock-knock mice were used to investigate the activation of the TLR4 channel in the periodontitis of the mouse and the expression of the nucleotide bonding receptor and oligomerization receptor Type 3 (NLRP3) Inflammasome, an upstream immune control point during the development of inflammation. The activation of TLR4 in a mouse periodontitis model has improved the expression of a secret phenotype (SAP) associated with senescence, which has stimulated the inflammation process. Conversely, the TLR4 activation has reduced the expression of the leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia leukemia 1 (BMI-1) and has promoted the initiation of NLRP3 inflammor, both of which are Saem regulators.

Gingival Fibroblast Treatment with BMI-1 Inhibitor PTC209, TLR4 has been shown to activate the NLRP3 channel and the inflammation process by deleting BMI-1. In addition, there was a significant reduction in the expression of the BMI-1 expression in gingiva patients with periodontitis compared to healthy controls. In conclusion, this study demonstrated that TLR4 acted by inhibiting BMI-1 to improve the lane of NLRP3 and SAP factors. This reaction waterfall can contribute to the periodontium senescence. The family of toll receptors (TLR) is composed of essential receptors responsible for the recognition of diagrams in innate immunity, making it the essential proteins involved in the detection of pathogens and by providing immune responses. The most studied member of this family, TLR4, was the focus of attention regarding its contributory role in many inflammatory diseases, including the sepsi shock and asthma. In particular, assembly evidence has proved that this receiver is aberrantly expressed on tumor cells and tumor microenvironment in a wide range of cancer types and is strongly associated with the initiation of tumorigenesis as well as the Progression of tumor and drug resistance.

 

 Low Maternal Dietary Intake of Choline Regulates <em>Toll</em>-<em>Like</em> <em>Receptor</em> <em>4</em> Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells
Low Maternal Dietary Intake of Choline Regulates TollLike Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells

<em> toll </ em> – <em> like </ em> <em> </ em> <em> 4 </ em> regulates intestinal fibrosis via cytokine expression and epithelial-mesenchymatory transition

The intestinal fibrosis induced by chronic and recurrent colitis, which is exacerbated by intestinal stenosis, stenosis and obstruction, is difficult to treat. The 4 (TLR4) toll receiver stimulates innate immunity and acquired in response to specific microbial components, but the role of TLR4 in intestinal fibrosis is largely unknown. We have examined its role in intestinal fibrosis using not only a model of murine fibrosis, but also human myofibroblasts and intestinal epithelial cells. Colon fibrosis has been induced in TLR4 deficient mice (TLR4 – / -) and its wild-type counterparts with 3% dextran sulphate. The absence of a TLR4 gene has mitigated chronic inflammation and infiltration of colic macrophages; Intestinal fibrosis and collagen deposition have been removed. In addition, the production of tumor necrosis factor-α, interleukin-12P40 and the transformant growth factor – β has been reduced in deficient macrophages of TLR4.

 

The TLR4 was silenced in CCD-18CO cells with a small interfering RNA (SIRNA) and the metalloproteinase-1 matrix, metalloproteinase tissue inhibitor and the collagenated α1 expression was evaluated. The role of TLR4 in the transition of epithelium-mesenchymates (EMT) was evaluated in HCT116 cells. Removal of SIRNAS TLR4 transcription affected myofibroblast activity, collagen synthesis and EMT in the human line of human cancer. Thus, we suggest that TLR4 can be an essential mediator in inflammation and intestinal chronic fibrosis, indicating that TLR4 signaling is a potential therapeutic target for intestinal fibrosis.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

20-abx313314
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

abx236948-100ug 100 ug
EUR 481

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody

20-abx174286
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Recombinant Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

4-RPB295Hu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Protein Tyrosine Phosphatase Receptor Type S expressed in: E.coli

Recombinant Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

4-RPB295Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Protein Tyrosine Phosphatase Receptor Type S expressed in: E.coli

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (Biotin)

20-abx274229
  • EUR 453.00
  • EUR 244.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (FITC)

20-abx274614
  • EUR 467.00
  • EUR 244.00
  • EUR 1386.00
  • EUR 648.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (HRP)

20-abx313315
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (FITC)

20-abx313316
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Antibody (Biotin)

20-abx313317
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein tyrosine phosphatase receptor-type S (PTPRS) polyclonal antibody

ABP-PAB-11050 100 ug Ask for price

Mouse Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Protein

20-abx068778
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Protein

20-abx167990
  • EUR 676.00
  • EUR 286.00
  • EUR 2082.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human)

4-PAB295Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

SEB295Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in tissue homogenates, cell lysates and other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

4-SEB295Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

20-abx152898
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) CLIA Kit

20-abx492605
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Protein Tyrosine Phosphatase Receptor Type S ELISA Kit (PTPRS)

RK02166 96 Tests
EUR 521

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RDR-PTPRS-Hu-48Tests 48 Tests
EUR 522

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RDR-PTPRS-Hu-96Tests 96 Tests
EUR 724

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RD-PTPRS-Hu-48Tests 48 Tests
EUR 500

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

RD-PTPRS-Hu-96Tests 96 Tests
EUR 692

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

DLR-PTPRS-Hu-48T 48T
EUR 498
Description: A sandwich quantitative ELISA assay kit for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) ELISA Kit

DLR-PTPRS-Hu-96T 96T
EUR 647
Description: A sandwich quantitative ELISA assay kit for detection of Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS) in samples from tissue homogenates, cell lysates or other biological fluids.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), APC

4-PAB295Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), Biotinylated

4-PAB295Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Biotin.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), Cy3

4-PAB295Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Cy3.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), FITC

4-PAB295Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with FITC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), HRP

4-PAB295Hu01-HRP
  • EUR 305.00
  • EUR 2714.00
  • EUR 772.00
  • EUR 383.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with HRP.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), PE

4-PAB295Hu01-PE
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with PE.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat)

4-PAB295Mu01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

Protein Tyrosine Phosphatase, Receptor Type, A Antibody

20-abx114876
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, E Antibody

20-abx114878
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, J Antibody

20-abx114881
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, M Antibody

20-abx114882
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, N Antibody

20-abx114883
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type, R Antibody

20-abx114884
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Receptor-type tyrosine-protein phosphatase zeta Antibody

20-abx109367
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase zeta Antibody

20-abx109368
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase R Antibody

20-abx110169
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-100

AR09-P0014-100 100ug
EUR 1388

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-25

AR09-P0014-25 25ug
EUR 528

protein tyrosine phosphatase, receptor type, S (PTPRS)(MBP-his tagged)-50

AR09-P0014-50 50ug
EUR 815

ELISA kit for Human PTPRS (Protein Tyrosine Phosphatase Receptor Type S)

ELK4856 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Protein Tyrosine Phosphatase Receptor Type S from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Human), APC-Cy7

4-PAB295Hu01-APC-Cy7
  • EUR 547.00
  • EUR 6106.00
  • EUR 1624.00
  • EUR 727.00
  • EUR 310.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC-Cy7.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), APC

4-PAB295Mu01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with APC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB295Mu01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Biotin.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB295Mu01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with Cy3.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB295Mu01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with FITC.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB295Mu01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with HRP.

Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody (Mouse, Rat), PE

4-PAB295Mu01-PE
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Protein Tyrosine Phosphatase Receptor Type S (PTPRS). This antibody is labeled with PE.

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx306795
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx149090
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx131177
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx131178
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx131180
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx131512
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx131513
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx131514
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type E (PTPRE) Antibody

20-abx131515
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type F (PTPRF) Antibody

20-abx131516
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type U (PTPRU) Antibody

20-abx131517
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Antibody

20-abx131518
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Antibody

20-abx131519
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Antibody

20-abx131546
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx134009
  • EUR 356.00
  • EUR 565.00
  • EUR 300.00
  • 100 ul
  • 200 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx134013
  • EUR 356.00
  • EUR 537.00
  • EUR 217.00
  • 100 ul
  • 200 ul
  • 30 ul

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx128746
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) Antibody

20-abx129111
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx129661
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx129751
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Antibody

20-abx129825
  • EUR 425.00
  • EUR 119.00
  • EUR 154.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 15 ug
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx130068
  • EUR 314.00
  • EUR 133.00
  • EUR 829.00
  • EUR 439.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

20-abx130337
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx130342
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

abx122351-100ug 100 ug
EUR 391

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx122352-100ug 100 ug
EUR 391

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx126438
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx126439
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx126440
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

20-abx127022
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody

20-abx128236
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase, Non-Receptor Type 11 Antibody

20-abx114867
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 14 Antibody

20-abx114868
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 2 Antibody

20-abx114870
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Non-Receptor Type 7 Antibody

20-abx114875
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx114886
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx117211-100ug 100 ug
EUR 467

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx136077
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

20-abx136151
  • EUR 495.00
  • EUR 356.00
  • 100 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

20-abx137094
  • EUR 356.00
  • EUR 523.00
  • 0.5 mg
  • 1 mg

Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) Antibody

20-abx124253
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx124267
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Receptor-type tyrosine-protein phosphatase R Antibody (FITC)

20-abx107285
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

20-abx104375
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104376
  • EUR 300.00
  • EUR 133.00
  • EUR 787.00
  • EUR 411.00
  • EUR 258.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104377
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104378
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx104379
  • EUR 328.00
  • EUR 815.00
  • EUR 425.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

20-abx104380
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody

20-abx104381
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx104382
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor-type tyrosine-protein phosphatase R Antibody (HRP)

20-abx108705
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

abx010527-100ul 100 ul
EUR 411

Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) Antibody

20-abx014804
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody

20-abx014805
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

20-abx006439
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Antibody

20-abx006633
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Antibody

20-abx006780
  • EUR 411.00
  • EUR 105.00
  • EUR 592.00
  • EUR 182.00
  • 100 ul
  • 10 ul
  • 200 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

20-abx006819
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx000698
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx001610
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

20-abx001727
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) Antibody

20-abx002368
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Protein Tyrosine Phosphatase Receptor Type U (PTPRU) Antibody

20-abx006232
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx026402-400ul 400 ul
EUR 523

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx026402-80l 80 µl
EUR 286

Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Antibody

abx016120-100ug 100 ug
EUR 411

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx021437-02mg 0.2 mg
EUR 481

Protein Tyrosine Phosphatase Receptor Type C (CD45) Antibody

abx021440-1mg 1 mg
EUR 968

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx028034-400ul 400 ul
EUR 523

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

abx028034-80l 80 µl
EUR 286

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

abx028113-400ul 400 ul
EUR 523

Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody

abx028113-80l 80 µl
EUR 286

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody

abx028322-400ul 400 ul
EUR 523

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody

abx028322-80l 80 µl
EUR 286

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

abx028663-400ul 400 ul
EUR 523

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

abx028663-80l 80 µl
EUR 286

Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody

abx431909-200ul 200 ul
EUR 286

Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Antibody

abx433203-200ul 200 ul
EUR 286

Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody

abx433204-200ul 200 ul
EUR 384

Receptor-Type Tyrosine-Protein Phosphatase T (PTPRT) Antibody

abx433205-200ul 200 ul
EUR 384

Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Antibody

abx445054-100ug 100 ug
EUR 523

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx270021
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx270028
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Protein Tyrosine Phosphatase Receptor Type C (PTPRC) Antibody

20-abx270143
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody

20-abx320358
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Protein Tyrosine Phosphatase, Receptor Type E (PTPRE) Antibody

20-abx320655
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Patients with type-2 diabetes mellitus (T2DM) have a low-quality chronic inflammation induced by activating the innate immune system. The toll receiver (TLR) 4 is a pattern recognition receiver that plays a vital role in activating the innate immune system. The results of the animal studies and the computer simulation computer have shown that the targeting of the TLR4 to block the TLR4-Nuclear Factor-Kappa B (NF-KB) route reduces the inflammatory response and the complications associated with T2DM . As a result, TLR4 targeted therapy has general prospects. Here we examined the role of TLR4 in inflammation during chronic hyperglycemia of T2DM and its therapeutic perspectives.

Leave A Comment